HTR2A anticorps (Internal Region)
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- Antigène Voir toutes HTR2A Anticorps
- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
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Épitope
- Internal Region
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HTR2A est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- 5HT2A Receptor Antibody detects endogenous levels of total 5HT2A Receptor.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human 5HT2A Receptor, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HTR2A Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
- Autre désignation
- HTR2A (HTR2A Produits)
- Synonymes
- anticorps 5-HT2A, anticorps HTR2, anticorps 5-HT-2, anticorps 5-HT-2A, anticorps 5-HTR2A, anticorps LOC100009461, anticorps E030013E04, anticorps Htr-2, anticorps Htr2, anticorps 5Ht-2, anticorps 5HT2A, anticorps 5HTR2A, anticorps HTR2A, anticorps Htr2a, anticorps 5HT2, anticorps 5-hydroxytryptamine receptor 2A, anticorps 5-hydroxytryptamine (serotonin) receptor 2A, anticorps HTR2A, anticorps Htr2a
- Sujet
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Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca2+ ions from intracellular stores (PubMed:18703043, PubMed:28129538). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
Gene: HTR2A
- Poids moléculaire
- 52 kDa
- ID gène
- 3356
- UniProt
- P28223
- Pathways
- Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
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