Adrenomedullin anticorps (N-Term)
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- Antigène Voir toutes Adrenomedullin (ADM) Anticorps
- Adrenomedullin (ADM)
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Adrenomedullin est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- ADM Antibody detects endogenous levels of total ADM.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human ADM, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ADM Anticorps primaire
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- Indications d'application
- WB 1:500-2000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- Adrenomedullin (ADM)
- Autre désignation
- ADM (ADM Produits)
- Synonymes
- anticorps ADM, anticorps Ap, anticorps H39316, anticorps RATAP, anticorps AM, anticorps adrenomedullin, anticorps ADM, anticorps adm, anticorps Adm
- Classe de substances
- Hormone
- Sujet
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Description: AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Gene: ADM
- Poids moléculaire
- 20 kDa
- ID gène
- 133
- UniProt
- P35318
- Pathways
- Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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