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ADRM1 anticorps (Internal Region)

Adrm1 Reactivité: Humain, Souris, Rat WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259812
  • Antigène Voir toutes ADRM1 (Adrm1) Anticorps
    ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))
    Épitope
    • 15
    • 14
    • 9
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 57
    • 16
    • 13
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 61
    • 4
    Lapin
    Clonalité
    • 62
    • 3
    Polyclonal
    Conjugué
    • 24
    • 7
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADRM1 est non-conjugé
    Application
    • 33
    • 30
    • 13
    • 13
    • 9
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    ADRM1 Antibody detects endogenous levels of total ADRM1.
    Homologie
    Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human ADRM1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product Adrm1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))
    Autre désignation
    ADRM1 (Adrm1 Produits)
    Synonymes
    anticorps arm-1, anticorps gp110, anticorps rpn13, anticorps xoom, anticorps ADRM1, anticorps adrm1, anticorps ARM-1, anticorps ARM1, anticorps GP110, anticorps 1110063P18Rik, anticorps 2510006J17Rik, anticorps AA408205, anticorps AU043535, anticorps Arm1, anticorps Gp110, anticorps Rpn13, anticorps adrm1a, anticorps adrm1b, anticorps fa12d09, anticorps wu:fa10g10, anticorps wu:fa12d09, anticorps zgc:56107, anticorps zgc:77256, anticorps adhesion regulating molecule 1, anticorps ADRM1, anticorps 19S proteasome regulatory subunit, anticorps ADRM1 protein, anticorps adrm1, anticorps ADRM1, anticorps CpipJ_CPIJ002929, anticorps SJAG_04211, anticorps Adrm1
    Sujet

    Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.

    Gene: ADRM1

    Poids moléculaire
    46 kDa
    ID gène
    11047
    UniProt
    Q16186
    Pathways
    Positive Regulation of Endopeptidase Activity
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