AFF4 anticorps (C-Term)

N° du produit ABIN6259815

Détail du produit anti-AFF4 anticorps

Antigène: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: AFF4 Antibody detects endogenous levels of total AFF4.

Homologie: Pig,Bovine,Horse,Sheep,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human AFF4, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur AFF4

Antigène: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Autre désignation: AFF4 (AFF4 Produits)

Synonymes: anticorps AFF4, anticorps RA_m002_jsmFBA6Br, anticorps AF5Q31, anticorps MCEF, anticorps Alf4, anticorps Laf4l, anticorps AF4/FMR2 family member 4 L homeolog, anticorps AF4/FMR2 family member 4, anticorps AF4/FMR2 family, member 4, anticorps aff4.L, anticorps AFF4, anticorps aff4, anticorps Aff4

Sujet:

Description: Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

Gene: AFF4

Poids moléculaire: 127kDa

ID gène: 27125

UniProt: Q9UHB7