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Angiopoietin 2 anticorps (N-Term)

ANGPT2 Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259925
  • Antigène Voir toutes Angiopoietin 2 (ANGPT2) Anticorps
    Angiopoietin 2 (ANGPT2)
    Épitope
    • 15
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 70
    • 35
    • 25
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 72
    • 10
    • 4
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 63
    • 26
    Polyclonal
    Conjugué
    • 47
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Angiopoietin 2 est non-conjugé
    Application
    • 58
    • 27
    • 27
    • 13
    • 13
    • 12
    • 10
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificité
    Angiopoietin 2 Antibody detects endogenous levels of total Angiopoietin 2.
    Homologie
    Pig
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Angiopoietin 2, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ANGPT2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Wu, Hu, Yin, Li, Zhang: "[Dose and timing of normal saline resuscitation on endothelial glycocalyx in early septic shock]." dans: Zhonghua wei zhong bing ji jiu yi xue, Vol. 30, Issue 7, pp. 629-634, (2018) (PubMed).

    Chen, Chen, Xu, Zhong, Zhang, Yang, Huang: "Electroacupuncture facilitates implantation by enhancing endometrial angiogenesis in a rat model of ovarian hyperstimulation." dans: Biology of reproduction, (2018) (PubMed).

  • Antigène
    Angiopoietin 2 (ANGPT2)
    Autre désignation
    ANGPT2 (ANGPT2 Produits)
    Sujet

    Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

    Gene: ANGPT2

    Poids moléculaire
    57 kDa
    ID gène
    285
    UniProt
    O15123
    Pathways
    Signalisation RTK
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