ARHGAP22 anticorps (C-Term)

N° du produit ABIN6260025

Détail du produit anti-ARHGAP22 anticorps

Antigène: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP22 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ARHGAP22 Antibody detects endogenous levels of total ARHGAP22.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ARHGAP22, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ARHGAP22

Antigène: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Autre désignation: ARHGAP22 (ARHGAP22 Produits)

Synonymes: anticorps si:ch211-223a10.2, anticorps RhoGAP2, anticorps RhoGap22, anticorps B230341L19Rik, anticorps RHOGAP2, anticorps p68RacGAP, anticorps Rho GTPase activating protein 22, anticorps rho GTPase activating protein 22, anticorps ARHGAP22, anticorps arhgap22, anticorps CC1G_06014, anticorps Arhgap22

Sujet:

Description: Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).

Gene: ARHGAP22

Poids moléculaire: 77kDa

ID gène: 58504

UniProt: Q7Z5H3