ARL3 anticorps (C-Term)
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- Antigène Voir toutes ARL3 Anticorps
- ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ARL3 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- ARL3 Antibody detects endogenous levels of total ARL3.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human ARL3, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ARL3 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))
- Autre désignation
- ARL3 (ARL3 Produits)
- Synonymes
- anticorps ARFL3, anticorps si:ch211-208d15.4, anticorps wu:fj22g05, anticorps arfl3, anticorps arl3, anticorps ADP ribosylation factor like GTPase 3, anticorps ADP-ribosylation factor-like 3, anticorps ADP ribosylation factor like GTPase 3 S homeolog, anticorps ADP-ribosylation factor-like protein 3, anticorps ARL3, anticorps arl3, anticorps Arl3, anticorps arl3.1.S, anticorps arl-3
- Sujet
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Description: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.
Gene: ARL3
- Poids moléculaire
- 20 kDa
- ID gène
- 403
- UniProt
- P36405
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