PYDC1 anticorps
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- Antigène Voir toutes PYDC1 Anticorps
- PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PYDC1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- ASC2 Antibody detects endogenous levels of total ASC2
- Réactivité croisée
- Humain, Souris, Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human ASC2
- Isotype
- IgG
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- Indications d'application
- WB 1:1000-3000 IHC 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
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- Antigène
- PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
- Autre désignation
- ASC2 (PYDC1 Produits)
- Synonymes
- anticorps ASC2, anticorps POP1, anticorps PYC1, anticorps pyrin domain containing 1, anticorps PYDC1
- Sujet
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Description: Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.
Gene: PYDC1
- Poids moléculaire
- 10 kDa
- ID gène
- 260434
- UniProt
- Q8WXC3
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