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BAG1 anticorps (N-Term)

BAG1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6260189
  • Antigène Voir toutes BAG1 Anticorps
    BAG1 (BCL2-Associated Athanogene (BAG1))
    Épitope
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 31
    • 18
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 27
    • 8
    Lapin
    Clonalité
    • 28
    • 7
    Polyclonal
    Conjugué
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BAG1 est non-conjugé
    Application
    • 28
    • 12
    • 10
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Bag 1 Antibody detects endogenous levels of total Bag 1.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Bag 1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product BAG1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    BAG1 (BCL2-Associated Athanogene (BAG1))
    Autre désignation
    BAG1 (BAG1 Produits)
    Synonymes
    anticorps BAG-1, anticorps HAP, anticorps RAP46, anticorps Rap46, anticorps Bag-1, anticorps ATBAG1, anticorps BCL-2-associated athanogene 1, anticorps MSG15.15, anticorps MSG15_15, anticorps im:7148830, anticorps si:dkey-216e9.4, anticorps BCL2 associated athanogene 1, anticorps putative bcl2-associated athanogene, anticorps BCL2-associated athanogene 1, anticorps Bcl2 associated athanogene 1, anticorps BAG family molecular chaperone regulator 1, anticorps BCL-2-associated athanogene 1, anticorps BAG1, anticorps Smp_005900, anticorps Bag1, anticorps bag-1, anticorps LOC781741, anticorps bag1
    Sujet

    Description: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:27474739, PubMed:9873016, PubMed:24318877). Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity (PubMed:12724406). Markedly increases the anti-cell death function of BCL2 induced by various stimuli (PubMed:9305631).

    Gene: BAG1

    Poids moléculaire
    31 kDa
    ID gène
    573
    UniProt
    Q99933
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