Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CBP anticorps (C-Term)

CREBBP Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6260516
  • Antigène Voir toutes CBP (CREBBP) Anticorps
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    Épitope
    • 11
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 85
    • 41
    • 36
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 81
    • 7
    Lapin
    Clonalité
    • 81
    • 7
    Polyclonal
    Conjugué
    • 42
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CBP est non-conjugé
    Application
    • 66
    • 44
    • 22
    • 19
    • 12
    • 12
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    CREB-BP Antibody detects endogenous levels of total CREB-BP.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CREB-BP, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CREBBP Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    Autre désignation
    CREBBP (CREBBP Produits)
    Synonymes
    anticorps CBP, anticorps KAT3A, anticorps RSTS, anticorps AW558298, anticorps CBP/p300, anticorps p300/CBP, anticorps RTS, anticorps cbp, anticorps crebbp, anticorps kat3a, anticorps rsts, anticorps hmm291030, anticorps Nejire, anticorps CREB binding protein, anticorps CREB binding protein L homeolog, anticorps histone acetyltransferase p300, anticorps CREBBP, anticorps Crebbp, anticorps crebbp.L, anticorps LOC100123220
    Sujet

    Description: Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).

    Gene: CREBBP

    Poids moléculaire
    265kDa
    ID gène
    1387
    UniProt
    Q92793
    Pathways
    TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
Vous êtes ici:
Support technique