CBX6 anticorps (N-Term)
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- Antigène Voir toutes CBX6 Anticorps
- CBX6 (Chromobox Homolog 6 (CBX6))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CBX6 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- CBX6 Antibody detects endogenous levels of total CBX6.
- Homologie
- Pig,Bovine,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human CBX6, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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- Indications d'application
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- CBX6 (Chromobox Homolog 6 (CBX6))
- Autre désignation
- CBX6 (CBX6 Produits)
- Synonymes
- anticorps cbx6, anticorps CBX6, anticorps zgc:101049, anticorps chromobox 6, anticorps chromobox 6 L homeolog, anticorps chromobox homolog 6a, anticorps cbx6, anticorps CBX6, anticorps Cbx6, anticorps cbx6.L, anticorps cbx6a
- Sujet
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Description: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity). May have a PRC1-independent function in embryonic stem cells (By similarity).
Gene: CBX6
- Poids moléculaire
- 44kDa
- ID gène
- 23466
- UniProt
- O95503
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