CCRN4L anticorps
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- Antigène Voir toutes CCRN4L Anticorps
- CCRN4L (CCR4 Carbon Catabolite Repression 4-Like (CCRN4L))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CCRN4L est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- CCRN4L Antibody detects endogenous levels of total CCRN4L
- Réactivité croisée
- Humain, Souris, Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human CCRN4L
- Isotype
- IgG
- Top Product
- Discover our top product CCRN4L Anticorps primaire
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- Indications d'application
- WB 1:1000-3000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
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- Antigène
- CCRN4L (CCR4 Carbon Catabolite Repression 4-Like (CCRN4L))
- Autre désignation
- CCRN4L (CCRN4L Produits)
- Synonymes
- anticorps CCR4L, anticorps NOC, anticorps AU043840, anticorps Ccr4, anticorps nocturnin, anticorps Ccrn4lb, anticorps MNOC, anticorps ccr4l, anticorps noc, anticorps MGC85016, anticorps ccrn4l, anticorps CCRN4L, anticorps nocturnin, anticorps nocturnin S homeolog, anticorps nocturnin L homeolog, anticorps putative nocturnin, anticorps NOCT, anticorps Noct, anticorps noct, anticorps noct.S, anticorps noct.L, anticorps LOC5570471, anticorps CpipJ_CPIJ011434, anticorps Smp_105040
- Sujet
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Description: Circadian deadenylase which plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Degrades poly(A) tails of specific target mRNAs leading to their degradation and suppression of translation. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. Plays an important role in favoring adipogenesis over osteoblastogenesis and acts as a key regulator of the adipogenesis/osteogenesis balance. Promotes adipogenesis by activating PPARG transcriptional activity in a deadenylase-independent manner by facilitating its nuclear translocation. Regulates circadian expression of NOS2 in the liver and negatively regulates the circadian expression of IGF1 in the bone. Critical for proper development of early embryos (By similarity).
Gene: NOCT
- Poids moléculaire
- 48 kDa
- ID gène
- 25819
- UniProt
- Q9UK39
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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