CDK13 anticorps (Internal Region)

N° du produit ABIN6260604

Détail du produit anti-CDK13 anticorps

Antigène: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK13 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CD2L5 Antibody detects endogenous levels of total CD2L5.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CD2L5, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CDK13

Antigène: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Autre désignation: CDK13 (CDK13 Produits)

Synonymes: anticorps CDC2L5, anticorps cdc2l5, anticorps wu:fe16d10, anticorps wu:fi49c05, anticorps CDC2L, anticorps CHED, anticorps hCDK13, anticorps 2310015O17Rik, anticorps Cdc2l5, anticorps cyclin dependent kinase 13, anticorps cyclin-dependent kinase 13, anticorps CDK13, anticorps cdk13, anticorps Cdk13

Sujet:

Description: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.

Gene: CDK13

Poids moléculaire: 165 kDa

ID gène: 8621

UniProt: Q14004