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CD46 anticorps (N-Term)

CD46 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6260628
  • Antigène Voir toutes CD46 Anticorps
    CD46
    Épitope
    • 16
    • 14
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 119
    • 33
    • 19
    • 10
    • 10
    • 3
    Humain, Souris, Rat
    Hôte
    • 82
    • 55
    • 2
    Lapin
    Clonalité
    • 72
    • 67
    Polyclonal
    Conjugué
    • 52
    • 16
    • 15
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD46 est non-conjugé
    Application
    • 85
    • 81
    • 42
    • 37
    • 30
    • 18
    • 14
    • 14
    • 12
    • 9
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    CD46 Antibody detects endogenous levels of total CD46.
    Homologie
    Sheep
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CD46, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CD46 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    CD46
    Autre désignation
    CD46 (CD46 Produits)
    Synonymes
    anticorps AHUS2, anticorps MCP, anticorps MIC10, anticorps TLX, anticorps TRA2.10, anticorps Mcp, anticorps CD46, anticorps CD46 molecule, anticorps CD46 antigen, complement regulatory protein, anticorps CD46 molecule, complement regulatory protein, anticorps membrane cofactor protein-like, anticorps CD46, anticorps Cd46, anticorps LOC100341359, anticorps LOC103789310
    Sujet

    Description: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.

    Gene: CD46

    Poids moléculaire
    43kDa
    ID gène
    4179
    UniProt
    P15529
    Pathways
    Regulation of Actin Filament Polymerization
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