CDT1 anticorps (C-Term)

N° du produit ABIN6260731

Détail du produit anti-CDT1 anticorps

Antigène: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDT1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: CDT1 Antibody detects endogenous levels of total CDT1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CDT1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CDT1

Antigène: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Autre désignation: CDT1 (CDT1 Produits)

Sujet:

Description: Required for both DNA replication and mitosis (PubMed:11125146, PubMed:22581055, PubMed:21856198, PubMed:14993212, PubMed:26842564). DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC)(PubMed:14672932). Required also for mitosis by promoting stable kinetochore-microtubule attachments (PubMed:22581055). Potential oncogene (By similarity).

Gene: CDT1

Poids moléculaire: 63 kDa

ID gène: 81620

UniProt: Q9H211

Pathways: Signalisation MAPK, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA