CISD2 anticorps (Internal Region)
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- Antigène Voir toutes CISD2 Anticorps
- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
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Épitope
- Internal Region
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CISD2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- CISD2 Antibody detects endogenous levels of total CISD2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human CISD2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product CISD2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
- Autre désignation
- CISD2 (CISD2 Produits)
- Synonymes
- anticorps ERIS, anticorps Miner1, anticorps NAF-1, anticorps WFS2, anticorps ZCD2, anticorps 1500009M05Rik, anticorps 1500026J14Rik, anticorps 1500031D15Rik, anticorps AI848398, anticorps B630006A20Rik, anticorps Noxp70, anticorps Zcd2, anticorps RGD1566242, anticorps zgc:64148, anticorps eris, anticorps miner1, anticorps wfs2, anticorps zcd2, anticorps cisd2, anticorps BcDNA:RE49709, anticorps Dmel\\CG1458, anticorps CDGSH iron sulfur domain 2, anticorps CDGSH iron sulfur domain 2 L homeolog, anticorps CDGSH iron sulfur domain 2 S homeolog, anticorps CISD2, anticorps Cisd2, anticorps cisd2, anticorps cisd2.L, anticorps cisd2.S
- Sujet
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Description: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca2+ stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
Gene: CISD2
- Poids moléculaire
- 13-15 kDa
- ID gène
- 493856
- UniProt
- Q8N5K1
- Pathways
- Activation of Innate immune Response
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