Calsyntenin 1 anticorps (C-Term)

N° du produit ABIN6260898

Détail du produit anti-Calsyntenin 1 anticorps

Antigène: Calsyntenin 1 (CLSTN1)

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calsyntenin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CLSTN1 Antibody detects endogenous levels of total CLSTN1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CLSTN1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Calsyntenin 1

Antigène: Calsyntenin 1 (CLSTN1)

Autre désignation: CLSTN1 (CLSTN1 Produits)

Synonymes: anticorps CALSYNTENIN-1, anticorps fm67g03, anticorps wu:fk52g02, anticorps wu:fm67g03, anticorps zgc:153744, anticorps zgc:56528, anticorps clstn1, anticorps 1810034E21Rik, anticorps Cst-1, anticorps Cstn1, anticorps ALC-ALPHA, anticorps CDHR12, anticorps CSTN1, anticorps PIK3CD, anticorps XB31alpha, anticorps alcalpha1, anticorps alcalpha2, anticorps calsyntenin 1, anticorps calsyntenin 3, anticorps beta-catenin-interacting protein 1, anticorps calsyntenin-1, anticorps CLSTN1, anticorps clstn1, anticorps clstn3, anticorps LOC100356725, anticorps LOC100435584, anticorps Clstn1, anticorps LOC479600

Sujet:

Description: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (By similarity).

Gene: CLSTN1

Poids moléculaire: 110 kDa

ID gène: 22883

UniProt: O94985