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CNGA3 anticorps (N-Term)

CNGA3 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6260908
  • Antigène Voir toutes CNGA3 Anticorps
    CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))
    Épitope
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 12
    • 12
    • 6
    • 2
    Humain
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CNGA3 est non-conjugé
    Application
    • 8
    • 6
    • 4
    • 1
    Western Blotting (WB), ELISA
    Specificité
    CNGA3 Antibody detects endogenous levels of total CNGA3.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CNGA3, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CNGA3 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))
    Autre désignation
    CNGA3 (CNGA3 Produits)
    Synonymes
    anticorps ACHM2, anticorps CCNC1, anticorps CCNCa, anticorps CCNCalpha, anticorps CNCG3, anticorps CNG3, anticorps CNGA3, anticorps cyclic nucleotide gated channel alpha 3, anticorps CNGA3, anticorps Cnga3
    Sujet

    Description: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

    Gene: CNGA3

    Poids moléculaire
    79 kDa
    ID gène
    1261
    UniProt
    Q16281
    Pathways
    Phototransduction
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