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Complexin 1 anticorps (N-Term)

CPLX1 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261003
  • Antigène Voir toutes Complexin 1 (CPLX1) Anticorps
    Complexin 1 (CPLX1)
    Épitope
    • 15
    • 14
    • 8
    • 7
    • 6
    • 6
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 49
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 52
    Polyclonal
    Conjugué
    • 14
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Complexin 1 est non-conjugé
    Application
    • 36
    • 22
    • 19
    • 13
    • 13
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    CPLX1 Antibody detects endogenous levels of total CPLX1.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CPLX1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CPLX1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    Complexin 1 (CPLX1)
    Autre désignation
    CPLX1 (CPLX1 Produits)
    Synonymes
    anticorps MGC84299, anticorps CPLX1, anticorps CPX-I, anticorps CPX1, anticorps 921-S, anticorps complexin 1 L homeolog, anticorps complexin 1, anticorps cplx1.L, anticorps CPLX1, anticorps cplx1, anticorps Cplx1
    Sujet

    Description: Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles (PubMed:21785414). Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse (PubMed:21785414). Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.

    Gene: CPLX1

    Poids moléculaire
    15-20 kDa
    ID gène
    10815
    UniProt
    O14810
    Pathways
    Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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