Cyclin A anticorps

N° du produit ABIN6261138

Détail du produit anti-Cyclin A anticorps

Antigène: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Specificité: Cyclin A antibody detects endogenous levels of total Cyclin A

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Cyclin A

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:3000 IHC: 1:50~1:200 IF/ICC: 1:100~1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Références pour anticorps anti-Cyclin A (ABIN6261138)

Liao, Xiao, Chen, Zhang, Chen, Long, Gao, He, Ge, Yi, Wu, Li, Zhou: "The receptor for activated protein kinase C promotes cell growth, invasion and migration in cervical cancer." dans: International journal of oncology, Vol. 51, Issue 5, pp. 1497-1507, (2018) (PubMed).

Huang, Song, Tao, Shao, Zeng, Xu, Qi, Sun: "Ovostatin 2 knockdown significantly inhibits the growth, migration, and tumorigenicity of cutaneous malignant melanoma cells." dans: PLoS ONE, Vol. 13, Issue 4, pp. e0195610, (2018) (PubMed).

Liao, Xiao, Chen, Zhang, Chen, Long, Gao, Zhu, He, Peng, Xiong, Zeng, Li, Zhou, Li, Ma, Wu, Xiang, Li, Zhou: "CD38 enhances the proliferation and inhibits the apoptosis of cervical cancer cells by affecting the mitochondria functions." dans: Molecular carcinogenesis, Vol. 56, Issue 10, pp. 2245-2257, (2017) (PubMed).

Chen, Suo, Cheng, Zheng, Xu: "Vascular endothelial growth factor C enhances cervical cancer migration and invasion via activation of focal adhesion kinase." dans: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, Vol. 29, Issue 1, pp. 20-4, (2013) (PubMed).

Détails sur Cyclin A

Antigène: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Autre désignation: Cyclin A (CCNA2 Produits)

Sujet:

Description: May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.

Gene: CCNA1

Poids moléculaire: 53kDa

ID gène: 8900

UniProt: P78396, P20248

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA