CYR61 anticorps (Internal Region)
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- Antigène Voir toutes CYR61 Anticorps
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CYR61 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- CYR61/CCN1 Antibody detects endogenous levels of total CYR61/CCN1.
- Homologie
- Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human CYR61/CCN1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product CYR61 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
- Autre désignation
- CYR61 (CYR61 Produits)
- Synonymes
- anticorps CCN1, anticorps GIG1, anticorps IGFBP10, anticorps ccn1, anticorps gig1, anticorps Xcyr61, anticorps igfbp10, anticorps MGC69281, anticorps MGC69539, anticorps cyr61-l2, anticorps zgc:158158, anticorps CYR61, anticorps AI325051, anticorps Igfbp10, anticorps cysteine rich angiogenic inducer 61, anticorps cysteine-rich, angiogenic inducer, 61, anticorps cysteine-rich, angiogenic inducer, 61 like 2, anticorps cysteine rich protein 61, anticorps cysteine rich angiogenic inducer 61 S homeolog, anticorps CYR61, anticorps Cyr61, anticorps cyr61, anticorps cyr61l2, anticorps cyr61.S
- Sujet
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Description: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
Gene: CYR61
- Poids moléculaire
- 42kDa
- ID gène
- 3491
- UniProt
- O00622
- Pathways
- Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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