DAPK2 anticorps (C-Term)

N° du produit ABIN6261222

Détail du produit anti-DAPK2 anticorps

Antigène: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAPK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: DAPK2 Antibody detects endogenous levels of total DAPK2.

Homologie: Pig,Horse,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DAPK2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DAPK2

Antigène: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Autre désignation: DAPK2 (DAPK2 Produits)

Synonymes: anticorps drp1, anticorps drp-1, anticorps DAPK2, anticorps dapk2, anticorps DRP-1, anticorps DRP1, anticorps death-associated protein kinase 2 L homeolog, anticorps death associated protein kinase 2, anticorps death-associated protein kinase 2b, anticorps death-associated protein kinase 2, anticorps dapk2.L, anticorps DAPK2, anticorps dapk2b, anticorps dapk2, anticorps Dapk2

Sujet:

Description: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).

Gene: DAPK2

Poids moléculaire: 42 kDa

ID gène: 23604

UniProt: Q9UIK4