DIO3 anticorps
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- Antigène Voir toutes DIO3 Anticorps
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DIO3 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- DIO3 Antibody detects endogenous levels of total DIO3
- Réactivité croisée
- Humain, Souris, Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human DIO3
- Isotype
- IgG
- Top Product
- Discover our top product DIO3 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
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- Antigène
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- Autre désignation
- DIO3 (DIO3 Produits)
- Synonymes
- anticorps 5DIII, anticorps DIOIII, anticorps txdi3, anticorps dioiii, anticorps XL-15, anticorps itdi3, anticorps D3, anticorps TXDI3, anticorps iodothyronine deiodinase 3, anticorps deiodinase, iodothyronine, type 3, anticorps deiodinase, iodothyronine, type III, anticorps deiodinase, iodothyronine type III, anticorps deiodinase, iodothyronine, type 3 L homeolog, anticorps DIO3, anticorps dio3, anticorps Dio3, anticorps dio3.L
- Sujet
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Description: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Gene: DIO3
- Poids moléculaire
- 31 kDa
- ID gène
- 1735
- UniProt
- P55073
- Pathways
- Hormone Activity
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