DNAJC3 anticorps (C-Term)
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- Antigène Voir toutes DNAJC3 Anticorps
- DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DNAJC3 est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- DNAJC3 Antibody detects endogenous levels of total DNAJC3.
- Homologie
- Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human DNAJC3, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product DNAJC3 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))
- Autre désignation
- DNAJC3 (DNAJC3 Produits)
- Synonymes
- anticorps ERdj6, anticorps HP58, anticorps P58, anticorps P58IPK, anticorps PRKRI, anticorps zgc:56356, anticorps zgc:77731, anticorps wu:fb64f06, anticorps DNAJC3, anticorps dnajc3, anticorps DDBDRAFT_0186884, anticorps DDBDRAFT_0233602, anticorps DDB_0186884, anticorps DDB_0233602, anticorps cg8286, anticorps AA408985, anticorps AU067833, anticorps Dnajc3a, anticorps Dnajc3b, anticorps Prkri, anticorps mp58, anticorps p58, anticorps p58IPK, anticorps fc17a06, anticorps prkri, anticorps wu:fc17a06, anticorps DnaJ heat shock protein family (Hsp40) member C3, anticorps DnaJ (Hsp40) homolog, subfamily C, member 3a, anticorps DNAJ heat shock N-terminal domain-containing protein, anticorps DnaJ heat shock protein family (Hsp40) member C3 L homeolog, anticorps DnaJ (Hsp40) homolog, subfamily C, member 3b, anticorps DNAJC3, anticorps dnajc3a, anticorps dnajc3, anticorps dnajc3.L, anticorps Dnajc3, anticorps dnajc3b
- Sujet
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Description: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Gene: DNAJC3
- Poids moléculaire
- 54 kDa
- ID gène
- 5611
- UniProt
- Q13217
- Pathways
- ER-Nucleus Signaling
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