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DOCK7 anticorps (N-Term)

DOCK7 Reactivité: Humain, Rat, Souris ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261348
  • Antigène Voir toutes DOCK7 Anticorps
    DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
    Épitope
    • 15
    • 5
    • 2
    • 2
    • 2
    N-Term
    Reactivité
    • 35
    • 16
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 33
    • 2
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DOCK7 est non-conjugé
    Application
    • 13
    • 13
    • 9
    • 7
    • 5
    • 3
    • 3
    • 1
    ELISA, Western Blotting (WB)
    Specificité
    DOCK7 Antibody detects endogenous levels of total DOCK7.
    Homologie
    Pig,Bovine,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human DOCK7, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product DOCK7 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
    Autre désignation
    DOCK7 (DOCK7 Produits)
    Synonymes
    anticorps im:7145816, anticorps im:7157388, anticorps wu:fb93h07, anticorps ZIR2, anticorps 3110056M06Rik, anticorps Gm430, anticorps m, anticorps mKIAA1771, anticorps dedicator of cytokinesis 7, anticorps dedicator of cytokinesis protein 7, anticorps dedicator of cytokinesis 6, anticorps DOCK7, anticorps dock7, anticorps NAEGRDRAFT_56982, anticorps LOC100185115, anticorps dock6, anticorps Dock7
    Sujet

    Description: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).

    Gene: DOCK7

    Poids moléculaire
    242kDa
    ID gène
    85440
    UniProt
    Q96N67
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