DOCK7 anticorps (N-Term)

N° du produit ABIN6261348

Détail du produit anti-DOCK7 anticorps

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK7 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: DOCK7 Antibody detects endogenous levels of total DOCK7.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DOCK7, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DOCK7

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Autre désignation: DOCK7 (DOCK7 Produits)

Synonymes: anticorps im:7145816, anticorps im:7157388, anticorps wu:fb93h07, anticorps ZIR2, anticorps 3110056M06Rik, anticorps Gm430, anticorps m, anticorps mKIAA1771, anticorps dedicator of cytokinesis 7, anticorps dedicator of cytokinesis protein 7, anticorps dedicator of cytokinesis 6, anticorps DOCK7, anticorps dock7, anticorps NAEGRDRAFT_56982, anticorps LOC100185115, anticorps dock6, anticorps Dock7

Sujet:

Description: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).

Gene: DOCK7

Poids moléculaire: 242kDa

ID gène: 85440

UniProt: Q96N67