DVL1 anticorps
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- Antigène Voir toutes DVL1 Anticorps
- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DVL1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificité
- DVL1 Antibody detects endogenous levels of total DVL1
- Réactivité croisée
- Humain, Souris, Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human DVL1
- Isotype
- IgG
- Top Product
- Discover our top product DVL1 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000 IHC 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
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- Antigène
- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
- Autre désignation
- DVL1 (DVL1 Produits)
- Synonymes
- anticorps DVL, anticorps DVL1L1, anticorps DVL1P1, anticorps Dvl, anticorps mKIAA4029, anticorps dvl-1, anticorps DSH, anticorps DVL-1, anticorps dvl1, anticorps dvl2l, anticorps Xdsh, anticorps dsh1, anticorps dishevelled segment polarity protein 1, anticorps dishevelled, dsh homolog 1 (Drosophila), anticorps microRNA 6808, anticorps dishevelled segment polarity protein 1b, anticorps dishevelled segment polarity protein 1 L homeolog, anticorps DVL1, anticorps Dvl1, anticorps MIR6808, anticorps dvl1b, anticorps dvl1.L
- Sujet
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Description: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
Gene: DVL1
- Poids moléculaire
- 75 kDa
- ID gène
- 1855
- UniProt
- O14640
- Pathways
- Signalisation WNT, Synaptic Membrane, Skeletal Muscle Fiber Development
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