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EEF2K anticorps (Internal Region)

EEF2K Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261444
  • Antigène Voir toutes EEF2K Anticorps
    EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))
    Épitope
    • 18
    • 13
    • 11
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 73
    • 38
    • 27
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 86
    • 2
    Lapin
    Clonalité
    • 88
    Polyclonal
    Conjugué
    • 46
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EEF2K est non-conjugé
    Application
    • 65
    • 36
    • 15
    • 15
    • 15
    • 13
    • 9
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    EEF2K Antibody detects endogenous levels of total eEF2K.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human eEF2K, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product EEF2K Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Deng, Luo, Lai, Song, Peng, Wei: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." dans: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).

  • Antigène
    EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))
    Autre désignation
    EEF2K (EEF2K Produits)
    Synonymes
    anticorps HSU93850, anticorps eEF-2K, anticorps C86191, anticorps SMEF2K, anticorps eEF-2 kinase, anticorps cb365, anticorps fa04b08, anticorps wu:fa04b08, anticorps zgc:100973, anticorps eukaryotic elongation factor 2 kinase, anticorps eukaryotic elongation factor-2 kinase, anticorps EEF2K, anticorps Eef2k, anticorps eef2k, anticorps LOC101930123
    Sujet

    Description: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

    Gene: EEF2K

    Poids moléculaire
    82kDa
    ID gène
    29904
    UniProt
    O00418
    Pathways
    AMPK Signaling
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