EEF2K anticorps (Internal Region)

N° du produit ABIN6261444

Détail du produit anti-EEF2K anticorps

Antigène: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EEF2K est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: EEF2K Antibody detects endogenous levels of total eEF2K.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human eEF2K, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-EEF2K (ABIN6261444)

Deng, Luo, Lai, Song, Peng, Wei: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." dans: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).

Détails sur EEF2K

Antigène: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Autre désignation: EEF2K (EEF2K Produits)

Synonymes: anticorps HSU93850, anticorps eEF-2K, anticorps C86191, anticorps SMEF2K, anticorps eEF-2 kinase, anticorps cb365, anticorps fa04b08, anticorps wu:fa04b08, anticorps zgc:100973, anticorps eukaryotic elongation factor 2 kinase, anticorps eukaryotic elongation factor-2 kinase, anticorps EEF2K, anticorps Eef2k, anticorps eef2k, anticorps LOC101930123

Sujet:

Description: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

Gene: EEF2K

Poids moléculaire: 82kDa

ID gène: 29904

UniProt: O00418

Pathways: AMPK Signaling