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N° du produit ABIN6261455
  • Antigène Voir toutes Ephrin B2 (EFNB2) Anticorps
    Ephrin B2 (EFNB2)
    Épitope
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 57
    • 34
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 52
    • 4
    • 1
    Lapin
    Clonalité
    • 45
    • 11
    Polyclonal
    Conjugué
    • 34
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp Ephrin B2 est non-conjugé
    Application
    • 34
    • 19
    • 12
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Ephrin B2 Antibody detects endogenous levels of total Ephrin B2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Ephrin B2, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    Ephrin B2 (EFNB2)
    Autre désignation
    EFNB2 (EFNB2 Produits)
    Synonymes
    anticorps EFNB2, anticorps efnb2, anticorps ephrin-B2, anticorps htkl, anticorps eplg5, anticorps htk-l, anticorps lerk5, anticorps ephrinB2, anticorps efnb2a, anticorps MGC68890, anticorps efnb2b, anticorps ELF-2, anticorps Epl5, anticorps Eplg5, anticorps Htk-L, anticorps LERK-5, anticorps Lerk5, anticorps NLERK-1, anticorps EPLG5, anticorps HTKL, anticorps LERK5, anticorps ephrin B2, anticorps ephrin-B2 precursor, anticorps ephrin B2 L homeolog, anticorps ephrin B2 S homeolog, anticorps EFNB2, anticorps efnb2, anticorps efnb2.L, anticorps efnb2.S, anticorps Efnb2
    Sujet

    Description: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

    Gene: EFNB2

    Poids moléculaire
    36kDa
    ID gène
    1948
    UniProt
    P52799
    Pathways
    Signalisation RTK, Regulation of Muscle Cell Differentiation
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