EHMT2 anticorps (N-Term)

N° du produit ABIN6261470

Détail du produit anti-EHMT2 anticorps

Antigène: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EHMT2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: EHMT2 Antibody detects endogenous levels of total EHMT2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human EHMT2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur EHMT2

Antigène: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Autre désignation: EHMT2 (EHMT2 Produits)

Synonymes: anticorps BAT8, anticorps C6orf30, anticorps G9A, anticorps GAT8, anticorps KMT1C, anticorps NG36, anticorps T27C4.12, anticorps T27C4_12, anticorps DL3235W, anticorps FCAALL.188, anticorps T18B16.120, anticorps T18B16_120, anticorps F9H3.13, anticorps F9H3_13, anticorps F9H3.7, anticorps F9H3_7, anticorps F9H3.9, anticorps F9H3_9, anticorps F9H3.6, anticorps F9H3_6, anticorps F13G24.40, anticorps T20K14.110, anticorps T20K14_110, anticorps MWD22.10, anticorps MWD22_10, anticorps MRB17.12, anticorps MRB17_12, anticorps MAF19.22, anticorps MAF19_22, anticorps Bat8, anticorps D17Ertd710e, anticorps G9a, anticorps Ng36, anticorps euchromatic histone lysine methyltransferase 2, anticorps ankyrin repeat-containing protein, anticorps Ankyrin repeat family protein, anticorps euchromatic histone lysine N-methyltransferase 2, anticorps EHMT2, anticorps ank1, anticorps IscW_ISCW006888, anticorps Arnit_2917, anticorps AT3G04470, anticorps AT4G14390, anticorps AT4G19150, anticorps AT4G03500, anticorps AT4G03450, anticorps AT4G03460, anticorps AT4G03440, anticorps PIA1, anticorps AT5G15500, anticorps AT5G51160, anticorps AT5G54620, anticorps ANK6, anticorps AT1G04780, anticorps AT1G62050, anticorps Ehmt2

Sujet:

Description: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.

Gene: EHMT2

Poids moléculaire: 132kDa

ID gène: 10919

UniProt: Q96KQ7