EIF3S1 anticorps (Internal Region)
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- Antigène Voir toutes EIF3S1 Anticorps
- EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EIF3S1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- EIF3J Antibody detects endogenous levels of total EIF3J.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human EIF3J, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product EIF3S1 Anticorps primaire
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- Indications d'application
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))
- Autre désignation
- EIF3J (EIF3S1 Produits)
- Synonymes
- anticorps GB12381, anticorps An18g06260, anticorps AO090003000054, anticorps EIF3S1, anticorps eIF3j, anticorps eIF3-alpha, anticorps eIF3-p35, anticorps Eif3s1, anticorps eif3s1, anticorps 1810016I04Rik, anticorps 2700079K05Rik, anticorps AA409117, anticorps AA409446, anticorps C78575, anticorps Eif3j, anticorps Eif3j-1, anticorps Eif3j-2, anticorps Eif3j2, anticorps eIF-3-alpha-A, anticorps eIF-3-alpha-B, anticorps eIF3j-A, anticorps eIF3j-B, anticorps eukaryotic translation initiation factor 3 subunit J, anticorps eukaryotic translation initiation factor 3, subunit J, anticorps Eukaryotic translation initiation factor 3 subunit J, anticorps eukaryotic translation initiation factor 3 subunit 1, anticorps eukaryotic translation initiation factor 3 subunit J S homeolog, anticorps eukaryotic translation initiation factor 3, subunit J1, anticorps LOC409796, anticorps ANI_1_830164, anticorps AOR_1_94154, anticorps Eif3j, anticorps EIF3J, anticorps eif3j, anticorps LOC733089, anticorps eif3j.S, anticorps Eif3j1
- Sujet
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Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Gene: EIF3J
- Poids moléculaire
- 29 kDa
- ID gène
- 8669
- UniProt
- O75822
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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