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EPH Receptor A3 anticorps (C-Term)

EPHA3 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261558
  • Antigène Voir toutes EPH Receptor A3 (EPHA3) Anticorps
    EPH Receptor A3 (EPHA3)
    Épitope
    • 20
    • 15
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 80
    • 58
    • 50
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 90
    • 5
    • 1
    Lapin
    Clonalité
    • 90
    • 6
    Polyclonal
    Conjugué
    • 40
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EPH Receptor A3 est non-conjugé
    Application
    • 61
    • 35
    • 21
    • 13
    • 13
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    EPHA3 Antibody detects endogenous levels of total EPHA3.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human EPHA3, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product EPHA3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    EPH Receptor A3 (EPHA3)
    Autre désignation
    EPHA3 (EPHA3 Produits)
    Synonymes
    anticorps EK4, anticorps ETK, anticorps ETK1, anticorps HEK, anticorps HEK4, anticorps TYRO4, anticorps EPHA3, anticorps AW492086, anticorps Cek4, anticorps End3, anticorps Hek, anticorps Hek4, anticorps Mek4, anticorps Tyro4, anticorps CEK4, anticorps EPH receptor A3, anticorps ephrin type-A receptor 3, anticorps Eph receptor A3, anticorps EPHA3, anticorps LOC100439679, anticorps Epha3
    Sujet

    Description: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

    Gene: EPHA3

    Poids moléculaire
    110 kDa
    ID gène
    2042
    UniProt
    P29320
    Pathways
    Signalisation RTK, Regulation of Cell Size
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