ETAA1 anticorps (Internal Region)
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- Antigène Tous les produits ETAA1
- ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))
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Épitope
- Internal Region
- Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ETAA1 est non-conjugé
- Application
- ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- ETAA1 Antibody detects endogenous levels of total ETAA1.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human ETAA1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
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- Indications d'application
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))
- Autre désignation
- ETAA1 (ETAA1 Produits)
- Synonymes
- anticorps ETAA16, anticorps ETAA1, anticorps 5730466H23Rik, anticorps AA672646, anticorps etaa1, anticorps MGC145507, anticorps MGC81344, anticorps RGD1560957, anticorps zgc:171518, anticorps ETAA1, ATR kinase activator, anticorps Ewing tumor-associated antigen 1, anticorps Ewing tumor associated antigen 1, anticorps ETAA1, ATR kinase activator L homeolog, anticorps ETAA1, anticorps Etaa1, anticorps etaa1, anticorps etaa1.L
- Sujet
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Description: Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717).
Gene: ETAA1
- Poids moléculaire
- 103 kDa
- ID gène
- 54465
- UniProt
- Q9NY74
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