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ETAA1 anticorps (Internal Region)

ETAA1 Reactivité: Humain, Souris ELISA, WB, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261612
  • Antigène Tous les produits ETAA1
    ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))
    Épitope
    • 2
    • 1
    Internal Region
    Reactivité
    Humain, Souris
    Hôte
    • 12
    Lapin
    Clonalité
    • 12
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ETAA1 est non-conjugé
    Application
    ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    ETAA1 Antibody detects endogenous levels of total ETAA1.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human ETAA1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Indications d'application
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))
    Autre désignation
    ETAA1 (ETAA1 Produits)
    Synonymes
    anticorps ETAA16, anticorps ETAA1, anticorps 5730466H23Rik, anticorps AA672646, anticorps etaa1, anticorps MGC145507, anticorps MGC81344, anticorps RGD1560957, anticorps zgc:171518, anticorps ETAA1, ATR kinase activator, anticorps Ewing tumor-associated antigen 1, anticorps Ewing tumor associated antigen 1, anticorps ETAA1, ATR kinase activator L homeolog, anticorps ETAA1, anticorps Etaa1, anticorps etaa1, anticorps etaa1.L
    Sujet

    Description: Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717).

    Gene: ETAA1

    Poids moléculaire
    103 kDa
    ID gène
    54465
    UniProt
    Q9NY74
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