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EYA2 anticorps (Internal Region)

EYA2 Reactivité: Humain, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261629
  • Antigène Voir toutes EYA2 Anticorps
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Épitope
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 41
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Rat
    Hôte
    • 53
    • 3
    Lapin
    Clonalité
    • 54
    • 2
    Polyclonal
    Conjugué
    • 20
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EYA2 est non-conjugé
    Application
    • 43
    • 25
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    EYA2 Antibody detects endogenous levels of total EYA2.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human EYA2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product EYA2 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Autre désignation
    EYA2 (EYA2 Produits)
    Synonymes
    anticorps EYA2, anticorps zgc:92279, anticorps eab1, anticorps Eab1, anticorps EAB1, anticorps EYA transcriptional coactivator and phosphatase 2, anticorps EYA2, anticorps eya2, anticorps Eya2
    Sujet

    Description: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (PubMed:12500905, PubMed:23435380). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19351884). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2, in this it is functionally redundant with EYA1 (PubMed:12500905).

    Gene: EYA2

    Poids moléculaire
    59 kDa
    ID gène
    2139
    UniProt
    O00167
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