FAIM3 anticorps (Internal Region)

N° du produit ABIN6261662

Détail du produit anti-FAIM3 anticorps

Antigène: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: FAIM3 Antibody detects endogenous levels of total FAIM3.

Homologie: Pig,Bovine,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human FAIM3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur FAIM3

Antigène: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Autre désignation: FCMR (FAIM3 Produits)

Synonymes: anticorps FAIM3, anticorps FCMR, anticorps TOSO, anticorps 1810037B05Rik, anticorps FcmuR, anticorps Toso, anticorps Fc fragment of IgM receptor, anticorps FCMR, anticorps Fcmr

Sujet:

Description: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Gene: FCMR

Poids moléculaire: 43 kDa

ID gène: 9214

UniProt: O60667