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GEMIN8 anticorps (C-Term)

GEMIN8 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261938
  • Antigène Voir toutes GEMIN8 Anticorps
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    Épitope
    • 8
    • 6
    • 6
    • 5
    C-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 28
    • 2
    Lapin
    Clonalité
    • 28
    • 2
    Polyclonal
    Conjugué
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GEMIN8 est non-conjugé
    Application
    • 19
    • 17
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité
    GEMIN8 Antibody detects endogenous levels of total GEMIN8.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human GEMIN8, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GEMIN8 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    Autre désignation
    GEMIN8 (GEMIN8 Produits)
    Synonymes
    anticorps FAM51A1, anticorps B130034M20Rik, anticorps B930082C09Rik, anticorps BC023488, anticorps gemin-8, anticorps gem nuclear organelle associated protein 8, anticorps gemin8, anticorps GEMIN8, anticorps Gemin8
    Sujet

    Description: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

    Gene: GEMIN8

    Poids moléculaire
    29kDa
    ID gène
    54960
    UniProt
    Q9NWZ8
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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