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GLI1 anticorps (C-Term)

GLI1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261968
  • Antigène Voir toutes GLI1 Anticorps
    GLI1 (Zinc Finger Protein GLI1 (GLI1))
    Épitope
    • 16
    • 14
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 83
    • 53
    • 34
    • 17
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    Humain, Souris, Rat
    Hôte
    • 70
    • 13
    • 3
    • 1
    Lapin
    Clonalité
    • 66
    • 21
    Polyclonal
    Conjugué
    • 40
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GLI1 est non-conjugé
    Application
    • 52
    • 18
    • 16
    • 14
    • 13
    • 12
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Gli1 Antibody detects endogenous levels of total Gli1.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Gli1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GLI1 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    GLI1 (Zinc Finger Protein GLI1 (GLI1))
    Autre désignation
    GLI1 (GLI1 Produits)
    Synonymes
    anticorps GLI, anticorps Gli, anticorps Gli-1, anticorps gli1.1, anticorps AV235269, anticorps Zfp-5, anticorps Zfp5, anticorps GLI family zinc finger 1, anticorps GLI family zinc finger 1 S homeolog, anticorps GLI-Kruppel family member GLI1, anticorps GLI1, anticorps Gli1, anticorps gli1.S, anticorps gli1
    Sujet

    Description: Acts as a transcriptional activator (PubMed:19706761, PubMed:10806483, PubMed:19878745, PubMed:24311597, PubMed:24217340). Binds to the DNA consensus sequence 5'-GACCACCCA-3' (PubMed:2105456, PubMed:8378770, PubMed:24217340). May regulate the transcription of specific genes during normal development (PubMed:19706761). May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling (PubMed:19706761). Plays a role in cell proliferation and differentiation via its role in SHH signaling (Probable).

    Gene: GLI1

    Poids moléculaire
    119 kDa
    ID gène
    2735
    UniProt
    P08151
    Pathways
    Signalisation Hedgehog, Dopaminergic Neurogenesis
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