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GZMB anticorps

GZMB Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262072
  • Antigène Voir toutes GZMB Anticorps
    GZMB (Granzyme B (GZMB))
    Reactivité
    • 130
    • 51
    • 24
    • 10
    • 4
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 82
    • 50
    • 3
    Lapin
    Clonalité
    • 80
    • 55
    Polyclonal
    Conjugué
    • 78
    • 12
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GZMB est non-conjugé
    Application
    • 70
    • 42
    • 41
    • 35
    • 18
    • 17
    • 15
    • 14
    • 13
    • 9
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Granzyme B antibody detects endogenous levels of total Granzyme B
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Granzyme B
    Isotype
    IgG
    Top Product
    Discover our top product GZMB Anticorps primaire
  • Indications d'application
    WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.Stable for 12 months from date of receipt
    Date de péremption
    12 months
  • Antigène
    GZMB (Granzyme B (GZMB))
    Autre désignation
    Granzyme B (GZMB Produits)
    Synonymes
    anticorps CCPI, anticorps CGL-1, anticorps CGL1, anticorps CSP-B, anticorps CSPB, anticorps CTLA1, anticorps CTSGL1, anticorps HLP, anticorps SECT, anticorps granzyme B, anticorps GZMB
    Sujet

    Description: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    Gene: GZMB

    Poids moléculaire
    28kDa
    ID gène
    3002
    UniProt
    P10144, P20718
    Pathways
    Apoptose, Caspase Cascade in Apoptosis
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