HDAC6 anticorps (N-Term)

N° du produit ABIN6262187

Détail du produit anti-HDAC6 anticorps

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: HDAC6 Antibody detects endogenous levels of total HDAC6.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HDAC6, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur HDAC6

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Autre désignation: HDAC6 (HDAC6 Produits)

Synonymes: anticorps HD6, anticorps Hd6, anticorps Hdac5, anticorps Sfc6, anticorps mHDA2, anticorps CG6170, anticorps DHDAC2, anticorps DmHDAC2, anticorps Dmel\\CG6170, anticorps HDAC, anticorps HDAC2, anticorps dHDAC2, anticorps dHDAC6, anticorps dmHDA404, anticorps hdac6, anticorps MGC53140, anticorps wu:fc31d02, anticorps dsim_GLEANR_17355, anticorps DsimGD17207, anticorps GD17207, anticorps HDAC6, anticorps ATHDA6, anticorps AXE1, anticorps HISTONE DEACETYLASE 6, anticorps MDC12.7, anticorps MDC12_7, anticorps RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1, anticorps RPD3B, anticorps RTS1, anticorps SIL1, anticorps histone deacetylase 6, anticorps histone deacetylase 6, anticorps Histone deacetylase 6, anticorps histone deacetylase 6 L homeolog, anticorps GD17207 gene product from transcript GD17207-RB, anticorps Histone DeAcetylase, anticorps HDAC6, anticorps Hdac6, anticorps hdac6.L, anticorps hdac6, anticorps Dsim\HDAC6, anticorps PTRG_03035, anticorps HDA6, anticorps hda-6

Sujet:

Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Gene: HDAC6

Poids moléculaire: 131kDa

ID gène: 10013

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling