HDAC7 anticorps (C-Term)

N° du produit ABIN6262190

Détail du produit anti-HDAC7 anticorps

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: HDAC7 Antibody detects endogenous levels of total HDAC7.

Homologie: Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HDAC7, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur HDAC7

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Autre désignation: HDAC7 (HDAC7 Produits)

Synonymes: anticorps HD7A, anticorps HDAC7A, anticorps 5830434K02Rik, anticorps HD7, anticorps HD7a, anticorps Hdac7a, anticorps mFLJ00062, anticorps hdac7a, anticorps K2K18.5, anticorps K2K18_5, anticorps histone deacetylase7, anticorps histone deacetylase 7, anticorps histone deacetylase7, anticorps HDAC7, anticorps Hdac7, anticorps hdac7, anticorps HDA7

Sujet:

Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).

Gene: HDAC7

Poids moléculaire: 103 kDa

ID gène: 51564

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development