HECTD1 anticorps

N° du produit ABIN6262200

Détail du produit anti-HECTD1 anticorps

Antigène: HECTD1 (HECT Domain Containing 1 (HECTD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HECTD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: HECTD1 Antibody detects endogenous levels of total HECTD1

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HECTD1

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur HECTD1

Antigène: HECTD1 (HECT Domain Containing 1 (HECTD1))

Autre désignation: HECTD1 (HECTD1 Produits)

Sujet:

Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.

Gene: HECTD1

Poids moléculaire: 289kDa

ID gène: 25831

UniProt: Q9ULT8

Pathways: Tube Formation, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2