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HIPK1 anticorps (N-Term)

HIPK1 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262240
  • Antigène Voir toutes HIPK1 Anticorps
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    Épitope
    • 15
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 53
    • 27
    • 16
    • 15
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 48
    • 5
    Lapin
    Clonalité
    • 49
    • 4
    Polyclonal
    Conjugué
    • 18
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HIPK1 est non-conjugé
    Application
    • 40
    • 24
    • 17
    • 13
    • 13
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Specificité
    HIPK1 Antibody detects endogenous levels of total HIPK1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human HIPK1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product HIPK1 Anticorps primaire
  • Indications d'application
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    Autre désignation
    HIPK1 (HIPK1 Produits)
    Synonymes
    anticorps HIPK1, anticorps myak, anticorps nbak2, anticorps hipk1, anticorps Myak, anticorps Nbak2, anticorps 1110062K04Rik, anticorps homeodomain interacting protein kinase 1, anticorps homeodomain interacting protein kinase 1 L homeolog, anticorps homeodomain interacting protein kinase 1 S homeolog, anticorps HIPK1, anticorps hipk1.L, anticorps hipk1, anticorps hipk1.S, anticorps Hipk1
    Sujet

    Description: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.

    Gene: HIPK1

    Poids moléculaire
    131 kDa
    ID gène
    204851
    UniProt
    Q86Z02
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