HNRNPD/AUF1 anticorps (Internal Region)
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- Antigène Voir toutes HNRNPD/AUF1 (HNRNPD) Anticorps
- HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HNRNPD/AUF1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- HnRPD Antibody detects endogenous levels of total hnRPD.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human hnRPD, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HNRNPD Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
- Autre désignation
- HNRNPD (HNRNPD Produits)
- Synonymes
- anticorps AUF1, anticorps AUF1A, anticorps HNRPD, anticorps P37, anticorps hnRNPD0, anticorps Auf1, anticorps Hnrnpd, anticorps HNRNPD, anticorps p37, anticorps auf1a, anticorps hnrpd, anticorps hnrnpd0, anticorps C230004L04, anticorps Hnrpd, anticorps wu:fa28b06, anticorps zgc:162951, anticorps heterogeneous nuclear ribonucleoprotein D, anticorps heterogeneous nuclear ribonucleoprotein D L homeolog, anticorps HNRNPD, anticorps Hnrnpd, anticorps hnrnpd, anticorps hnrnpd.L
- Sujet
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Description: Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation of the rhythmic expression of circadian clock core genes. Directly binds to the 3'UTR of CRY1 mRNA and induces CRY1 rhythmic translation. May also be involved in the regulation of PER2 translation.
Gene: HNRNPD
- Poids moléculaire
- 38kDa
- ID gène
- 3184
- UniProt
- Q14103
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