HORMAD1 anticorps (C-Term)

N° du produit ABIN6262338

Détail du produit anti-HORMAD1 anticorps

Antigène: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HORMAD1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: HORMAD1 Antibody detects endogenous levels of total HORMAD1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HORMAD1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur HORMAD1

Antigène: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Autre désignation: HORMAD1 (HORMAD1 Produits)

Synonymes: anticorps CT46, anticorps NOHMA, anticorps 4921522K05Rik, anticorps Nohma, anticorps RGD1564960, anticorps zgc:92129, anticorps HORMAD1, anticorps HORMA domain containing 1, anticorps HORMA domain containing 1 S homeolog, anticorps HORMAD1, anticorps Hormad1, anticorps hormad1, anticorps hormad1.S

Sujet:

Description: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.

Gene: HORMAD1

Poids moléculaire: 45kDa

ID gène: 84072

UniProt: Q86X24

Pathways: M Phase