HSPA2 anticorps
-
- Antigène Voir toutes HSPA2 Anticorps
- HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp HSPA2 est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Specificité
- HSPA2 Antibody detects endogenous levels of total HSPA2
- Réactivité croisée
- Humain
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human HSPA2
- Isotype
- IgG
- Top Product
- Discover our top product HSPA2 Anticorps primaire
-
-
- Indications d'application
- WB 1:1000-3000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C.Stable for 12 months from date of receipt
- Date de péremption
- 12 months
-
- Antigène
- HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))
- Autre désignation
- HSPA2 (HSPA2 Produits)
- Synonymes
- anticorps HSP70-2, anticorps HSP70-3, anticorps HSPA2, anticorps DKFZp468B217, anticorps 70kDa, anticorps HSP70.2, anticorps HSP70A2, anticorps Hsp70-2, anticorps Hspt70, anticorps Hst70, anticorps HSPA3, anticorps heat shock protein family A (Hsp70) member 2, anticorps heat shock protein Hsp20, anticorps heat shock 70kDa protein 2, anticorps heat shock protein 2, anticorps heat shock protein family A member 2, anticorps HSPA2, anticorps hspA2, anticorps Hspa2
- Sujet
-
Description: Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed:26865365). Plays a role in spermatogenesis. In association with SHCBP1L may participate in the maintenance of spindle integrity during meiosis in male germ cells (By similarity).
Gene: HSPA2
- Poids moléculaire
- 70 kDa
- ID gène
- 3306
- UniProt
- P54652
-