Kallikrein 7 anticorps (Internal Region)

N° du produit ABIN6262851

Détail du produit anti-Kallikrein 7 anticorps

Antigène: Kallikrein 7 (KLK7)

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: Kallikrein 7 Antibody detects endogenous levels of total Kallikrein 7.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Kallikrein 7, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Kallikrein 7

Antigène: Kallikrein 7 (KLK7)

Autre désignation: KLK7 (KLK7 Produits)

Synonymes: anticorps Prss6, anticorps SCCE, anticorps PRSS6, anticorps hK7, anticorps kallikrein related-peptidase 7 (chymotryptic, stratum corneum), anticorps kallikrein-related peptidase 7, anticorps kallikrein related peptidase 7, anticorps Klk7, anticorps KLK7

Sujet:

Description: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.

Gene: KLK7

Poids moléculaire: 27kDa

ID gène: 5650

UniProt: P49862

Pathways: Système du Complément