Lactate Dehydrogenase A anticorps (C-Term)

N° du produit ABIN6262941

Détail du produit anti-Lactate Dehydrogenase A anticorps

Antigène: Lactate Dehydrogenase A (LDHA)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lactate Dehydrogenase A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: LDHA Antibody detects endogenous levels of total LDHA.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human LDHA, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-Lactate Dehydrogenase A (ABIN6262941)

Zhang, Wang, Han: "MicroRNA‑34a inhibits liver cancer cell growth by reprogramming glucose metabolism." dans: Molecular medicine reports, Vol. 17, Issue 3, pp. 4483-4489, (2018) (PubMed).

Zhang, Song, Sun, Li, Chen, Yang, Xing: "AMPK/GSK3β/β-catenin cascade-triggered overexpression of CEMIP promotes migration and invasion in anoikis-resistant prostate cancer cells by enhancing metabolic reprogramming." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 7, pp. 3924-3935, (2018) (PubMed).

Huang, Li, Xie, Ye, Chen, Song, Tang, Xie: "High expressions of LDHA and AMPK as prognostic biomarkers for breast cancer." dans: Breast (Edinburgh, Scotland), Vol. 30, pp. 39-46, (2017) (PubMed).

Xiao, Huang, Ye, Chen, Song, Wen, Zhang, Zheng, Tang, Xie: "The miR-34a-LDHA axis regulates glucose metabolism and tumor growth in breast cancer." dans: Scientific reports, Vol. 6, pp. 21735, (2016) (PubMed).

Détails sur Lactate Dehydrogenase A

Antigène: Lactate Dehydrogenase A (LDHA)

Autre désignation: LDHA (LDHA Produits)

Synonymes: anticorps GSD11, anticorps LDH1, anticorps LDHM, anticorps LDH-M, anticorps ldh-h, anticorps ldha, anticorps ldha-B, anticorps ldhbb, anticorps trg-5, anticorps Ldh1, anticorps Ldhm, anticorps l7R2, anticorps gsd11, anticorps ldh-m, anticorps ldh1, anticorps ldhm, anticorps pig19, anticorps ldha1, anticorps ldhab, anticorps LDH-A, anticorps LDHC, anticorps lactate dehydrogenase A, anticorps lactate dehydrogenase B L homeolog, anticorps lactate dehydrogenase A4, anticorps lactate dehydrogenase A L homeolog, anticorps L-lactate dehydrogenase A chain, anticorps LDHA, anticorps ldhb.L, anticorps Ldha, anticorps ldha, anticorps ldha.L, anticorps LOC100713875

Sujet:

Description: (S)-lactate + NAD+ = pyruvate + NADH.

Gene: LDHA

Poids moléculaire: 37kDa

ID gène: 3939

UniProt: P00338

Pathways: L'effet Warburg