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LIG3 anticorps (Internal Region)

LIG3 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6262966
  • Antigène Voir toutes LIG3 Anticorps
    LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))
    Épitope
    • 12
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 48
    • 15
    • 15
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 45
    • 3
    Lapin
    Clonalité
    • 46
    • 2
    Polyclonal
    Conjugué
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LIG3 est non-conjugé
    Application
    • 34
    • 19
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    DNA Ligase III Antibody detects endogenous levels of total DNA Ligase III.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human DNA Ligase III, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product LIG3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))
    Autre désignation
    LIG3 (LIG3 Produits)
    Synonymes
    anticorps orf36, anticorps DDBDRAFT_0218523, anticorps DDBDRAFT_0232266, anticorps DDB_0218523, anticorps DDB_0232266, anticorps LIG3, anticorps wu:fb12c02, anticorps wu:fd10b03, anticorps wu:fm79b09, anticorps LIG2, anticorps D11Wsu78e, anticorps An02g06890, anticorps AO090003000668, anticorps lig3, anticorps DNA ligase III, anticorps BRCT domain-containing protein, anticorps DNA ligase 3, anticorps ligase III, DNA, ATP-dependent, anticorps ligase III, DNA, ATP-dependent L homeolog, anticorps orf36, anticorps lig3, anticorps LIG3, anticorps Lig3, anticorps Bm1_22840, anticorps ANI_1_2644024, anticorps AOR_1_1174154, anticorps LOC100634887, anticorps lig3.L
    Sujet

    Description: Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627).

    Gene: LIG3

    Poids moléculaire
    113kDa
    ID gène
    3980
    UniProt
    P49916
    Pathways
    Réparation de l'ADN
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