LRPPRC anticorps (Internal Region)

N° du produit ABIN6263011

Détail du produit anti-LRPPRC anticorps

Antigène: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRPPRC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: LRPPRC Antibody detects endogenous levels of total LRPPRC.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human LRPPRC, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur LRPPRC

Antigène: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Autre désignation: LRPPRC (LRPPRC Produits)

Synonymes: anticorps CLONE-23970, anticorps GP130, anticorps LRP130, anticorps LSFC, anticorps Lrp157, anticorps 3110001K13Rik, anticorps C76645, anticorps Gp130, anticorps Lrp130, anticorps Lsfc, anticorps leucine rich pentatricopeptide repeat containing, anticorps leucine-rich pentatricopeptide repeat containing, anticorps leucine-rich PPR-motif containing, anticorps LRPPRC, anticorps Lrpprc

Sujet:

Description: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

Gene: LRPPRC

Poids moléculaire: 130 kDa

ID gène: 10128

UniProt: P42704