MAP1B anticorps (Internal Region)

N° du produit ABIN6263094

Détail du produit anti-MAP1B anticorps

Antigène: MAP1B (Microtubule-Associated Protein 1B (MAP1B))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP1B est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Specificité: MAP1B Antibody detects endogenous levels of total MAP1B.

Homologie: Pig,Zebrafish,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MAP1B, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MAP1B

Antigène: MAP1B (Microtubule-Associated Protein 1B (MAP1B))

Autre désignation: MAP1B (MAP1B Produits)

Sujet:

Description: Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.

Gene: MAP1B

Poids moléculaire: 320 kDa

ID gène: 4131

UniProt: P46821

Pathways: Dynamique des Microtubules, Regulation of Cell Size