MCM10 anticorps (C-Term)

N° du produit ABIN6263157

Détail du produit anti-MCM10 anticorps

Antigène: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: MCM10 Antibody detects endogenous levels of total MCM10.

Homologie: Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MCM10, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MCM10

Antigène: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Autre désignation: MCM10 (MCM10 Produits)

Synonymes: anticorps CG9241, anticorps DmMCM10, anticorps Dmel\\CG9241, anticorps Scim19, anticorps mcm10, anticorps CNA43, anticorps DNA43, anticorps xmcm10, anticorps 2410041F14Rik, anticorps AU018508, anticorps C330019M07Rik, anticorps C79164, anticorps Minichromosome maintenance 10, anticorps minichromosome maintenance 10 replication initiation factor, anticorps minichromosome maintenance 10 replication initiation factor L homeolog, anticorps Mcm10, anticorps MCM10, anticorps mcm10.L

Sujet:

Description: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability, acts as a direct target of transcriptional repression by ZBTB38 (PubMed:24726359).

Gene: MCM10

Poids moléculaire: 97-105 kDa

ID gène: 55388

UniProt: Q7L590

Pathways: Mitotic G1-G1/S Phases, DNA Replication